Dr Caroline Dewar
Lecturer in ParasitologyResearch Overview
My laboratory investigates the fundamental cellular mechanisms involved in maintaining mitochondrial function. Mitochondria are hubs for energy generation, metabolic and cell death pathways, thus guarding over the critical balance between cellular survival and death. Mitochondrial dysfunction has a central role in neurodegenerative and cardiovascular disorders, cancers and metabolic diseases.
Our research is focussed on understanding the pathways which counteract mitochondrial dysfunction in African trypanosomes, devastating parasites of both humans and cattle in sub-Saharan Africa. By studying these fascinating evolutionarily-diverged eukaryotes, we can shed light on the underlying features of mitochondrial quality control pathways, while also informing parasite drug discovery.
PhD Supervision Interests
I would be happy to hear from prospective students at PhD or MSc by Research level to discuss projects in trypanosome mitochondrial biology. Please contact me for further details: c.dewar1@lancaster.ac.uk.
Furness STEM show 2025
School Engagement
Journal of The Royal Society Interface (Journal)
Publication peer-review
PDRA Independent Fellowship Masterclass
Participation in workshop, seminar, course
Lancaster Biosciences Network Symposium
Symposium
University of York
Visiting an external academic institution
VEuPathDB Parasite Omics Workshop, Liverpool
Participation in workshop, seminar, course
RCAD Annual Career Development Workshop
Participation in workshop, seminar, course
FURNESS STEM SHOW 2023
Other
Parasites and Vectors (Journal)
Editorial activity
UlverSTEM 2022
Types of Public engagement and outreach - Festival/Exhibition
13th MaxQuant Summer School on Computational Mass Spectrometry-Based Proteomics, Barcelona
Participation in workshop, seminar, course
RCAD Annual Career Development Workshop
Participation in workshop, seminar, course
British Society for Parasitology Spring Meeting 2022, York
Participation in conference - Academic
Grant reviewer for NSERC
Other
PLoS Neglected Tropical Diseases (Journal)
Publication peer-review
- Microbes, Pathogens and Immunity