Dr Caroline Dewar

Lecturer in Parasitology

Research Overview

My laboratory investigates the fundamental cellular mechanisms involved in maintaining mitochondrial function. Mitochondria are hubs for energy generation, metabolic and cell death pathways, thus guarding over the critical balance between cellular survival and death. Mitochondrial dysfunction has a central role in neurodegenerative and cardiovascular disorders, cancers and metabolic diseases.

Our research is focussed on understanding the pathways which counteract mitochondrial dysfunction in African trypanosomes, devastating parasites of both humans and cattle in sub-Saharan Africa. By studying these fascinating evolutionarily-diverged eukaryotes, we can shed light on the underlying features of mitochondrial quality control pathways, while also informing parasite drug discovery.

Furness STEM show 2025
School Engagement

Journal of The Royal Society Interface (Journal)
Publication peer-review

PDRA Independent Fellowship Masterclass
Participation in workshop, seminar, course

Lancaster Biosciences Network Symposium
Symposium

University of York
Visiting an external academic institution

VEuPathDB Parasite Omics Workshop, Liverpool
Participation in workshop, seminar, course

RCAD Annual Career Development Workshop
Participation in workshop, seminar, course

FURNESS STEM SHOW 2023
Other

Parasites and Vectors (Journal)
Editorial activity

UlverSTEM 2022
Types of Public engagement and outreach - Festival/Exhibition

13th MaxQuant Summer School on Computational Mass Spectrometry-Based Proteomics, Barcelona
Participation in workshop, seminar, course

RCAD Annual Career Development Workshop
Participation in workshop, seminar, course

British Society for Parasitology Spring Meeting 2022, York
Participation in conference - Academic

Grant reviewer for NSERC
Other

PLoS Neglected Tropical Diseases (Journal)
Publication peer-review

  • Microbes, Pathogens and Immunity