Extracellular matrix

A complex network of usually insoluble macromolecules made up of water, ions, fibrous and adhesive proteins, and long-chain sugars (polysaccharides) that is dispersed in the spaces between cells and tissues of the body, and in which cells are embedded.  Thus, it is often referred to as a ‘biological glue’ as it is a source of structural support in tissue.  It provides a regulated environment that is crucial to the functioning of cells, such as neurons, and plays an important role in embryonic development.  It also forms part of connective tissues such bone and skin. 

See Adhesion molecules, Axon pathway selection, Collagen, Electrolyte, Fibroblasts, Filopodia, Growth cone, Integrins, Lamillpodia, Ligands, Oligodendrocytes, Ossification