An important component of the limbic system, it is a gyrus in the medial part of the brain that partially wraps around corpus callosum, which is constrained from above by the cingulate sulcus, and located between this sulcus and that of the corpus callosum. It receives inputs from the anterior nucleus of the thalamus and the neocortex, projects to the entorhinal cortex via the cingulum, and forms part of thecortico-basal-ganglionic-thalamic circuit. The cingulate cortex is the cortical part of the cingulated gyrus. It functions include the coordination of sensory input with emotions, emotional responses stress, and the regulation of aggressive behavior. Its increased activation is associated with obsessive-compulsive disorder and cue-related cocaine cravings, and disruptions of its connections during development with schizophrenia.
See Aggressive behaviour, Amygdala, Anterior cingulate gyrus, Corpus callosum, Entorhinal cortex, Gyrus, Limbic system, Obsessive-compulsive disorder (OCD), Orbitofrontal cortex, Pulvinar, Sulcus, Thalamus