A unilateral periventricular lesion of the brain where an schema of the brain is complicated by a hemorrhage. It is a neuropathological consequence of bleeding in the germinal matrix (a tissue with small, fragile blood vessels situated mainly in the periventricular regions of the head of the caudate nucleus in the thalamus), which is referred to as germinal-matrix intraventricular haemorrhage (IVH). It seldom occurs in infants born more than 30 weeks gestation. For those born at less than 30 weeks, however, and also for those with a birthweight of less 1500 grams, it can occur in up to 50% of cases.
See Caudate nucleus, Cerebral palsy, Ischemia, Periventricular leucomalacia (PVL), Preterm infants