Angelman’s syndrome

A genetic disorder dominated by learning disability, ataxia, jerky puppet-like movements, epilepsy, and various behaviour problems, including some autistic features; associated with loss of maternal alleles on chromosome 15q11-13 and other genetic abnormalities (see figure below).  Some 75% of those with the syndrome have a similar defect as found in the Prader-Willi syndrome, but occurring …

Anemia

A condition in which there is a low red blood cell count in the blood, usually marked by a decrease in hemoglobin, the pigment in red blood cells that transports oxygen.  It can be caused by many different conditions, including iron deficiency.  Symptoms may include fatigue, weakness, headache, and dizziness.  Common in pregnancy, it is …

Androgen

First discovered in 1936, it is a male sex steroid hormone in vertebrates produced by the testes and to a lesser extent by the adrenal cortex, such as testosterone, that controls the development and maintenance of sexual organs and secondary sexual characteristics in males.  Also called androgenic hormone and testoid. See Adolescent growth spurt, Adolescent …

Anaphase

Discounting interphase in meiosis, the third stage of cell division in the first division of meiosis (following prophase and the first metaphase).  In the first anaphase of meiosis, the paired homologous chromosomes separate and the half chromosomes move to opposite ends of the spindle.  In the second anaphase of the second division of meiosis, the …

Amygdala

Also called the amygdaloid nucleus, it is a key, almond-shaped, bilateral structure in the limbic system of the forebrain (see figure below), involved in emotion recognition and other social emotional functions such as fear, aggression and defensive behaviours, as well as learning and memory.  Connected with the prefrontal cortex, hypothalamus, hippocampus and cingulate gyrus.  Many …