Babbling

Frames, then content (FC) hypothesisNon-meaningful sound sequences produced by infants, especially sequences of consonants and vowels that typically appear between 6 and 10 months of age.  At first, babbling is relatively unformed.  It begins around 5 to 7 months of age, when a infant’s vocalisations start to appear as consonant-vowel combinations called canonical syllables, some …

Axon retraction (or pruning)

A phenomenon often seen in early normal development, and as with axonal proliferation occurring before birth, where axons extend farther, or to more places or terminal zones, than they will at maturity.  They then refine their connections by retracting.  Examples include the retraction of corpus callosum collaterals and the elimination of cortical-cortical connections (e.g., layer …

Axon hillock

The conical, tapering area of the axon’s origin from the soma of the neuron (see figure below), and contains microtubules as well as being devoid of Nissl substance.  It is here that the graded inputs of inhibitory postsynaptic potentials and excitatory postsynaptic potentials from the dendrites are summated to determine whether an action potential is …

Axon

Nerve cell process transporting outgoing or efferent information away from the cell body (or soma) in the form of an action potential toward a specific target (other neurons; gland; muscle) with which it connects by means of a synapse.  Sometimes referred to as a nerve fiber.  An axon of a motoneuron can be up to …

Axillary hair

Hair in the armpits (or axilla); a secondary sex characteristic.  In puberty, axillary hair usually appears after pubic hair.  In males, its appearance is associated with characteristic body odor, lowering of the voice pitch, and acne. See Adolescent growth spurt, Adolescent voice change, Pitch, Puberty, Secondary sexual characteristics

Autosomal dominant condition/disease

Genetic condition caused by one mutated gene located on one of the autosomal (‘non-sex’) chromosomes.  One of the parents will usually have the disease as it is dominant in this mode of inheritance.  Each child of an affected individual has a 50% chance of being affected, regardless of sex or birth order, and homozygotes for …