Four nuclei located deep in the cerebellar hemispheres, namely, the dentate nucleus (the largest), the globose emboliform nucleus and fastigial nucleus (which together form the nucleus interpositus), and the globose nucleus (see figure below). All are relay stations for the Purkinje cells from different cerebellar regions. The dentate nucleus receives inputs from the Purkinje cells in the lateral cortex of the cerebellum and has outputs to the ventrolateral thalamus, the cerebellar cortex (which is involved in sensorimotor coordination along with the motor cortex), the reticular formation, the oculomotor nucleus, and the red nucleus through the superior cerebral penduncle. The emboliform and the globose nuclei are the targets of Purkinje cell inputs from the intermediate cortex, and send their outputs to the cerebral cortex and the red nucleus, also via the superior cerebellar peduncle. The fastigial nuclei receive input from the cerebellar cortex covering the vermis, and send efferents to the vestibular nuclei, reticular formation and thalamus through the inferior cerebral penduncle.
