A 74 amino-acid substance that presynaptically blocks neuromuscular transmission. It is one of the so-called curare mimetic α-neurotoxins, which are among the most lethal constituents of venom in the snake Bungarus multicinctus. These toxins bind with very high affinities and selectivities to the nicotinic acetylcholine receptor (AcChoR), and in doing so block neuromuscular transmission through preventing the depolarising action on postsynaptic membranes.
See Acetylcholine (AcH), Akinesis, Amino acids, Botulinus (or botulinum or botox).