Adherent Skin Cells
Fibroblasts are cells that create and maintain the extracellular matrix (ECM) of connective tissues, providing structural support for organs and tissues. NIH 3T3 cells are a mouse embryonic fibroblast cell line commonly used in life science research. The original 3T3 cell line was established in 1962 by George Todaro and Howard Green at New York University School of Medicine. Fibroblasts form connections with their surroundings, spreading across surfaces. These cells have been labeled with green and red fluorescent proteins to reveal the full extent of their interaction with the underlying substrate.